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PubMed PMID: 4696188

As one of the most requested B12 formats, methylcobalamin is often selected by clients who want a naturally occurring ready to use form of B12 that bypasses digestive absorption

Conflicts of interest The authors declare no competing financial interest

Moreover, a US national study of 2,806 older women (50 years) found increased plasma concentration of methylmalonic acid the metabolic indicator of vitamin B 12 deficiency to be associated with increased risk of lumbar spine osteoporosis (115)

The Day14 samples from the nine subjects who did not develop acne after supplementation were clustered outside of the acne group