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Therefore, in a GSHcompromised system, the increase in the rate of formation of disulphide bonds is accompanied by an increase in the time required for isomerization

A preclinical study using a mouse model of ATC demonstrated that a ketogenic diet could suppress tumor growth, reduce tumor volume, lower lactate production, and increase apoptosis in malignant cells

doi: 10.2174/0929867327666200207114658 6 BanjacAPerisicTSatoHSeilerABannaiSWeissNet al

What your describing is not uncommon because methylation process is so complex & you may be deficient in other co-factors, such as B6, B2, Same, B12, etc Too much 5MTHF can drive overmethylation or dampen glutathione production and lead to agitation, irritability

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