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Targeting antioxidants specifically to the mitochondria is of particular interest, given that more than 80% of reactive oxygen species (ROS) are generated at this site

Hepatocyte ballooning was classified as 0 (none), 1 (few), or 2 (many cells/prominent ballooning)

This can result in cell membrane damage, DNA mutations and fibrosis

Available human studies are characterized by relatively small sample sizes, heterogeneity in dosing regimens, and short intervention durations, which restrict the ability to draw firm conclusions regarding efficacy and optimal therapeutic windows

Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape

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