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At the same time, OS can promote the proliferation of theca-interstitial cells, upregulate CYP17, reduce serum SHBG levels, increase androgen secretion, improve the biological activity of serum free testosterone, and cause HA
Yoneyama, M
Wang, P., K
These symptoms are generally not specific, but when they occur together, they can become noticeable
10.1038/nrendo.2017.151 7
Specifically, vanilloids treatment increased intracellular ROS, total iron, and Fe + levels, and reduced the expression of ferroptosis marker proteins SLC7A11 and GPX4
