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doi: 10.2147/JIR.S439217 184 ReisACAlessandriALAthaydeRMPerezDAVagoJPvilaTVet al

Haptoglobin and hemopexin molecules circulating in blood scavenge Hb and heme, respectively, to reduce their toxicity [223]

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REDEFINE 1 and REDEFINE 2 are completed phase 3 trials published in NEJM with over 4,600 participants

Using in vitro studies, more than 60 cell lines were tested for the toxicity to high dosages of ascorbate

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