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See the review in reference 4 for details and additional references on this topic

However, unlike the consistent long-term effect induced by L-NAME retrobulbar application, there was only limited detrimental retinal effect at 40 min after intravitreous L-NAME application in cats lasting only for 180 min [179]

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But for some athletes, PT alone brings them to 70-80% recovery and then plateaus

10.1038/sj.bjc.6605192 208 Prasad PandaS.KesharwaniA