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This article provides a concise overview of the molecular mechanisms involved in mitochondrial biogenesis, mitophagy, and mitochondrial dynamics, explores their interactions, and summarizes current research progress in understanding the mitochondrial quality control system in the context of neurodegenerative diseases

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Laboratory studies reveal TB-500 reduces production of inflammatory mediators including TNF- and IL-1 by 55% while enhancing anti-inflammatory IL-10 and TGF- expression, creating balanced immune responses that clear damaged tissue while supporting regeneration