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On day 14, there is still an infiltration of inflammatory cells in controls, presented moderate edema which disappears not before the day 28 (Figure 9), sustainable, but delayed discrete increase of vascularity with the discrete proliferation of fibroblast and production of reticulin and collagen fibers making loose connective tissue with mesh-like fibers, areolar tissue

in case of persistence of symptoms up to school age, this could explain the observed relationship

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Oxidative stress is a fundamental concept in biology introduced by the first time by Sies (2015)

The rate-limiting enzyme of the oxidative part of the PPP is G6P dehydrogenase (G6PD), which catalyzes the reaction between G6P and NADP +