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Finerenone offers dual benefits of antifibrotic and immunomodulatory effects, making it a recommended option for prioritized use in DKD patients with coexisting cardiovascular risks

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This work was supported by National Heart, Lung, and Blood Institute grant HL173818 (Q-KT), National Institute on Alcohol Abuse and Alcoholism grant AA031063 (DC), and Iowa Osteopathic and Educational Research grant IOER122204 (Q-KT)

While the study did not directly measure fat loss, elevated GH is well known to promote fat breakdown (lipolysis), providing a biological rationale for weight-loss claims

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Mechanisms of tumor necrosis factor--induced interleukin-6 synthesis in glioma cells