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It was seen that curcumin administration for one month remarkably restored the impaired cerebrovascular endothelium-dependent vasorelaxation in aging rats and up-regulated UCP2 and reduced ROS production, thus representing a promising lifestyle intervention for preventing age-related cerebrovascular disturbances

& Mowla, S

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Structural basis of the Integrator complex assembly and association with transcription factors

UQ is a naturally occurring vitamin-like molecule formed from redox-active benzoquinone head group conjugated to a poly-isoprenoid side chain of species-specific length (610 subunits) (Wang and Hekimi, 2016)