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3 Early screening and detection of methylation markers in cancer 3.1 Digestive system cancer 3.1.1 Colorectal cancer (CRC) According to the 2020 Global Cancer Data Statistics, colorectal cancer ranks third among common cancers worldwide and second among cancer-related mortality worldwide (Sung et al., 2021)

Plasma, urine and liver tissues were profiled using untargeted MS methods, which detected both primary and secondary bile acids

Inflamm Bowel Dis 13:269277

doi: 10.1146/annurev.food.102308.124101

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