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Lower-dose loading schedules (100500 g/day) were also reported, particularly in less severe cases, and a few patients received intravenous high-dose B12 of 1,000 g every other day for 3 weeks

Pregnant mothers in resource poor settings are at risk for poor vitamin B 12 status

The Ottawa Hospital Sterne JA, Hernn MA, Reeves BC et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions

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Frequency changes across the cycle, not the dose size

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