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Description
Note: MDPI stays neutral with regard to jurisdictional claims in published Chunarkar-Patil P et al (2024) Anticancer drug discovery based on natural products: from computational approaches to clinical studies

The GPX family contains eight members (GPX1-GPX8), of which GPX1-GPX4 and GPX6 (human) members have an active center of selenocysteine, which is an important selenoprotein in mammals (Table 1)

The druglike and orally bioavailable compounds identified herein are active in animal models of schistosomiasis with a broader range of developmental stages targeted than the drug of choice, PZQ

doi:10.1007/s10815-019-01464-3

These effects collectively contribute to reproductive toxicity

10.1007/s00280-017-3441-3 108 ParienteR.BejaranoI.RodrguezA
