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Zinc can modulate the activity of the MAPK pathway at multiple levels [125, 126]

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They found that under laser irradiation, with its great photothermal conversion efficiency, it could generate considerable heat, causing cell death in more than 70% of HT-29 human colorectal adenocarcinoma cells (while cisplatin exerted a small anti-tumor effect)

(1982) assessed decreased GH secretion (0.1 U/kg) 1 year after over 2 weeks of cranial irradiation in the monkeys (Chrousos et al., 1982)