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The MR-Egger intercept method was used to test horizontal pleiotropy

They were Group 1: the control group (without treatment), group 2: the sham group, normal saline (solvent of the MSG and L-carnitine), group 3: the healthy group (L-Ca 200) (received the L-carnitine 200 mg/kg b.w), group 4: MSG 3 g/kg b

The increased stiffness of ECM tissue is a result of dysregulated collagen cross-linking, which is related to post-translational modification of collagen involved in lysyl oxidase-like (LOXL) 2 and LOXL3 (Jones et al., 2018)

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Cancer Drug Targets 12 , 197209 (2012)

Occasional reports of acquired 5-oxoprolinemia and 5-oxoprolinuria have attributed the disorder to the administration of several drugs other than acetaminophen