oxidised glutathione definition oxidized (GSSG) Oxidation-reduction pathway of reduced glutathione

doi: 10.1038/ejcn.2016.249 16 NakayamaYKawasakiNTamiyaTAnzaiSToyoharaKNishiyamaAet al

While such alterations are broadly observed across malignant cells, CSCs appear to leverage these mechanisms distinctively to sustain their stem-like properties and drive aggressive tumor behavior

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These metabolites participate in a so-called free radical scavenging cascade, wherein they act either sequentially or in concert, and may synergize with other antioxidants like vitamins C, E, and glutathione [15,16,17]