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All experiments were performed in triplicates using 200 000 cells per well
In addition to iron overload, lipid peroxidation is an essential process for the development of ferroptosis [131]
Similarly, TFEB-mediated autophagy played a crucial role in the protective effects of UA in BV2 cells by upregulating the expressions of Beclin-1, LAMP1, and the LC3II/I ratio, while the knockdown of TFEB by siRNA markedly decreased autophagy activity in A + UA-treated BV2 cells
This is especially meaningful for cats with kidney disease, as it can prevent their already-damage kidneys from taking further harm and improve their decreased kidney functions
The Journal of Biological Chemistry, 278, 2082120827
[DOI] [PubMed] [Google Scholar] 37.Mazidi M, Rezaie P, Banach M
