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Research has shown that people who take metformin to treat insulin resistance caused by type 2 diabetes may be at risk of developing a vitamin B12 deficiency

Because NNMT activity has been associated with metabolic efficiency and cellular energy balance, researchers continue to explore how modulation of this enzyme may influence broader metabolic and biochemical pathways

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To date, metformin remains the first-line oral glucose-lowering drug used for the treatment of type 2 diabetes thanks to its well-established long-term safety and efficacy profile

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