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We summarize key mechanisms of action, categorize clinically relevant peptide classes, and address current limitations, including gaps in human data, safety considerations, and regulatory ambiguity

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Mechanistically, these changes appear to coincide with elevated NAD+ and activation of metabolic gene programs consistent with increased energy expenditure

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40 Oxalic acid in the colonized group was significantly higher than the control group (Figure 4) (137.7 vs 72.6 mmol/mol of creatinine) (p value=0.0029)
