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Probiotic bacteria as potential detoxification tools: assessing their heavy metal binding isotherms

Among endogenous compounds, casomorphinsopioid peptides derived from casein (a milk protein)are of particular interest, as they have been shown to both modulate pain signaling [166,167] and support wound healing [168]

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While preliminary evidence supports the adjunctive use of microbiota-targeted therapies alongside conventional hormone replacement, challenges such as individualized intervention design, optimization of microbial formulations, and integration of dietary modulation must be addressed