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Tian et al., 2025)

The use of Semaglutide / Cyanocobalamin Injection in pediatric populations has not been established, and the medication should not be used in patients under 18 years of age unless specifically justified by exceptional circumstances and under close specialist supervision

The biological basis for this lies in neuroinflammation, driven by the unique anatomical pathway between the sinuses and the brain

The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells