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doi: 10.1016/j.jfca.2025.107288 62 WangZZhaoFWeiPChaiXHouGMengQ

This dopaminergic deficit disrupts basal ganglia circuitry, impairing motor function and contributing to the core symptoms of the disease

In addition, poor solubility, limited BBB penetration, and low oral bioavailability-coupled with significant inter-individual variability in absorption and metabolism-pose substantial barriers to dose standardization and reproducibility

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The influence of age on some ocular basement membranes