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For those with severe deficiencies, higher doses may be required initially to replenish B12 levels
As an essential amino acid, it cannot be synthesized de novo by the human body due to a lack of the require metabolic pathway needed for its synthesis
Thevis, M (2017)

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Preservation of Insulin and Glucose Homeostasis Unlike growth hormone, which can cause insulin resistance and elevated blood glucose (diabetogenic effects), AOD-9604 has demonstrated no negative effects on carbohydrate metabolism
