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Date: February 25, 2011 Event: Eleventh Annual Biology Student Research Symposium Location: Dickinson College Caroline Elizabeth Gorn Immunofluorescent characterization of CO2-activated neurons in the RTN of the mouse brainstem

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The MnSOD gene polymorphism (Val16Ala, also referred to as Val9Ala in some studies) results in an Ala variant at position 9 in the mature protein (position 16 in the precursor protein) that increases the efficiency at which MnSOD is transported into the mitochondria, theoretically promoting hydrogen peroxide generation in this organelle (381)

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[3] Beyond its direct antimicrobial effects, LL-37 has immunomodulatory functions

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