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doi: 10.3389/fendo.2023.1230646

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M.SilvaJ.SanchezA.GarciaJ

In an open-label phase II trial, curcumin treatment (8 g/day) in combination with the anticancer drug gemcitabine was associated with severe abdominal pain in 7 out of 17 patients with advanced pancreatic cancer, leading to the treatment being discontinued in five patients while curcumin dosage was reduced to 4 g/day in two patients (79)

The specific activities of the enzymes involved in GSH, Cys and Met metabolism will be determined along with the levels of specific intermediate metabolites in different tissues

Near-critical GLUT1 and neurodegeneration