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Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors

Most patients use 1 ml injections two to three times per week

Endocr J 54(3):471476 Diekman MJ, van der Put NM, Blom HJ, Tijssen JG, Wiersinga WM (2001) Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism
Protein Misfolding and Aggregation in Alzheimer's Disease and Type 2 Diabetes Mellitus. CNS & Neurological DisordersDrug TargetsCNS & Neurological Disorders 13: 12801293

When 5-AR is activated, calmodulin-dependent protein kinase II (CaMKII) regulates calcium channels and RyR2 via PKA-dependent phosphorylation, thereby driving Ca 2+ accumulation (146)

[PMC free article: PMC3770071] [PubMed: 23434634] 771
