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The chronic inflammation seen in RA triggers a series of interconnected reactions, leading to the migration of white blood cells to inflamed joints
Protective effect of quercetin on hyperglycemia, oxidative stress and DNA damage in alloxan induced type 2 diabetic mice

Serum Lactate is another crucial marker, with elevated levels indicating impaired tissue perfusion and mitochondrial dysfunction, often correlating with worse outcomes

Glutathione is often called the bodys master antioxidant because it helps neutralise free radicals and reduce oxidative stress

If a significant part of this mechanism relies on re-absorption from bile that would be an issue due to lack of intrinsic factor breaking the "enterohepatic recirculation"

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