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Figure 1 and Table 2 have been included to represent schematically IGF-1 actions in metabolism with target organs

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Notably, treatment with APR-017 alone affected neither ROS level nor cell viability, while treatment with IC261 alone slightly elevated ROS level and reduced cell viability

A loss of red blood cell production will create symptoms of low energy and inability to concentrate

To test our hypothesis, we studied the functional role of miR-483-3p in modulating NK cell cytotoxic activity using a gain-of-function approach