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Through a systematic and comprehensive analysis of the multi-dimensional functions, heterogeneous regulation and roles in therapeutic resistance of the SSP across cancer types, this review aims to elucidate the conserved principles and cancer-specific characteristics of the SSP as a metabolic hub

Intestinal serotonergic alteration together with the increase in proinflammatory cytokines also generates chronic inflammation, resulting in decreased acid secretion, breakdown of the intestinal barrier, decreased expression of enzymes necessary to digest carbohydrates, and alteration of the intestinal adaptive immune system, leading to the appearance of food intolerances and bacterial overgrowth in the small intestine

By reducing lipid hydroperoxides in the presence of ferrous iron, Fer-1 prevents lipid membrane damage and exerts potent anti-ferroptotic effects (59)

Genistein induces receptor and mitochondrial pathways and increases apoptosis during BCL-2 knockdown in human malignant neuroblastoma SK-N-DZ cells

Injuries such as sciatic nerve damage, shoulder injury related to vaccine administration (SIRVA), and localized tissue necrosis are often preventableyet they continue to occur due to poor technique, inadequate training, or improper site selection