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doi:10.1016/j.biomaterials.2017.05.040 47

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One milligram per week is considered the therapeutic threshold for meaningful weight loss in clinical studies

Homocysteine is an amino acid that, when elevated, increases the risk of dementia, heart disease, and stroke, so lowering its levels via this conversion is beneficial

Conflating the two risks overstating the scientific and regulatory support for these compounds

Because of this, doctors and researchers are still collecting long-term data on people who use the medication for several years
