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PRLMs and tumor immunoregulation Besides their established role in regulating tumor angiogenesis, PRLMs shape tumor initiation and progression through diverse immunoregulatory mechanisms

Sato et al., 2011)

Our studies of chronic myeloid leukemia show that among the patients Pgp expressing cells disappear under therapy using drugs that are Pgp substrates (instead of multiplying under these conditions) [33]

Male mice underwent rapid loss of survival at extended time points, while female mice were largely unaffected

Yonehara S