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SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis

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To enhance clinical outcomes while ensuring product standardization and safety, these findings suggests the need for GMP-driven manufacturing optimization and rational combination strategies

Kolker S, Koeller DM, Okun JG, Hoffmann GF: Pathomechanisms of neurodegeneration in glutaryl-CoA dehydrogenase deficiency

Elevated ROS levels can lead to oxidative damage to DNA, proteins, and lipids, as well as mitochondrial dysfunction, in which finally result in cell death [2, 4]

Ngoruh A
