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Worthy of mention, a rise in the prevalence of subclinical autoimmune hypothyroidism and thyroid autoantibodies has been reported after iodine supplementation in iodine-deficient countries, likely in relation to enhanced immunogenicity of thyroglobulin [27]

Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord

Dev Biol

Roles of Raf/MEK/ERK and PI3K/Akt/mTOR pathways in prevention of apoptosis and induction of drug resistance in myeloid hematopoietic cells

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Thus, it is thought that ERdj5 recognizes misfolded substrates by virtue of their association with EDEM, reduces them, and then transfers them to the ERAD machinery