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Hypoxia induces M2 macrophages to express VSIG4 and mediate cardiac fibrosis after myocardial infarction

There is also the case of addictive drugs: for example, cocaine is known to decrease the livers GSH content and has been found to be conjugated with GSH, highlighting that cocaine impairment of protein thiols can be a molecular mechanism of its toxicity [139]

Journal of Clinical Medicine, 13 (13), 3741

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