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Description
Methods Enzymol 105:121126
In both circulation and local tissues, 90% of IGF1 binds to IGFBP3 to inhibit its binding to IGF1R, thereby prolonging the half-life of the IGF1 (Tannenbaum et al., 1983)
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The concept of using glycolysis inhibitors combined with chemotherapeutic drugs has already been proposed (24,65)
150 , 2494S2505S (2020)
Drug therapy replaced the use of KD over the following decades (37, 38)
