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Devalia V, Hamilton MS, Molloy AM

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Among them, the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B), mitogen-activated protein kinase/activator protein-1 (MAPK/AP-1), and the Janus kinase signal transducer and activator of transcription (JAK-STAT) pathways have been identified as the targets of luteolin [40, 4652]
Also, negative role of AtGSTU17 toward drought and salt stresses has been determined by the mutant analysis

A recent network meta-analysis took into consideration all the available treatments for UC (except ustekinumab) and concluded that tofacitinib is an efficacious treatment for moderate-to-severe active UC and is likely to be a cost-effective use of NHS resources[105]
