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GSH-EE serves as a precursor for GSH biosynthesis, thereby increasing the levels of thiols in lungs, and inhibiting oxidative insults

doi: 10.1016/j.tox.2006.10.013

Berberine also reduces apoptosis by modulating the PI3K/Akt and p38-MAPK pathways (Han et al., 2023)
Disorders of the gut-heart axis are characterized by alterations in intestinal permeability and disruption of the microbiome

the review employed pre-determined search criteria that included meta-analyses, systematic reviews, literature reviews, and case reports freely available in full text
