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Discovery of a potent, selective, and orally bioavailable c-met inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)

As a recognized Selank nootropic , it is primarily investigated for its anxiolytic (anti-anxiety) and mild cognitive-enhancing effects, offering a unique dual benefit

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Results: We included 3836 patients with sCeAD (median age = 46 years, 45% female), of whom 318 (8.3%) had FMD

Not using full protocol Mistake : Stopping after 1-2 weeks when feeling better

This distinction matters for recovery quality and long-term outcomes