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doi: 10.1016/j.jff.2024.106627 62 ZorovD

Furthermore, a third melatonin-binding site (MT3) has been characterized and identified as the cytosolic enzyme quinone reductase 2 (QR2), a known detoxifying enzyme that reduces menadione and other quinones 26,27

Active sites of thioredoxin reductases: why selenoproteins

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Through the compartmentalization of energy requirements, the glycolytic ATP supports membrane potential maintenance, required for the effective depolarization process, while ATP generated by oxidative phosphorylation is utilized for cellular contractility mechanisms [32]

[DOI] [PMC free article] [PubMed] [Google Scholar] 173.Whitaker LHR, Middleton LJ, Daniels JP, et al