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Its uncommon because B12 is water-soluble, and excess amounts leave the body naturally

In addition, most of these molecules are characterized by rapid hepatic and renal clearance and inadequate passive transport across cell membranes
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Did you know that recent research shows thattaking B12 in a sublingual oral form is more effective for treating B12 deficiencies than actually getting B12 intramuscular shots? It's usually much more convenient and affordable as well -
Contribution to alterations of vasomotor tone
