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Although the pathogenesis of these diseases is not fully understood, several neurological components have been already identified as responsible for the neuronal pathology such as increased protein aggregates, glial activation/inflammation, mitochondrial dysfunction, disbalance of neurotransmitters, autophagia or oxidative stress (Figure 1)

Naorem L, Muthaiyan M, Venkatesan A
In addition, it also helps compare two newer alternatives for treatment, namely, curcumin and glutathione

Educators can try building 3D models where the different side chains of proteins can be demarcated and their respective interactions with other side chains of the same protein and those on the different polypeptide chains can be studied

Int J Neuropsychopharmacol 25(1):4653 ahin TD, Karson A, Balc F, Yazr Y, Bayramgrler D, Utkan T (2015) TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression
S., Dunleavy, J
