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In women with PMOS, kisspeptin signalling is dysregulated

Moreover, nanoparticles based on lipids or polymers cannot be directly quantified in tissue sample or homogenate, and they must be measured using indirect methods, commonly assessing the small molecule or the genetic material that is encapsulated in the particles

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It also leads to a significant increase in serum ALT and total nitrate/nitrite, hepatic lipid peroxides, and depletion of hepatic GSH and ATP (96)
