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Description
The formulated nanoparticles significantly attenuated t-BOOHinduced cytotoxicity across multiple brain-derived cell lines and exhibited superior permeability across an in vitro BBB model (Papp 80 10 6 cm/s) relative to unencapsulated phytoconstituents (Papp 50 10 6 cm/s) (152)
10.3389/fonc.2022.1013035 55 GuerraF.ArbiniA
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Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells
As cell surface receptors, GPCRs transduce a wide range of stimuli across membranes which triggers diverse downstream signalling cascades affecting many physiological processes 2
by utilizing this vulnerability of tumor cells, the SGN1 strain, which expresses L-methioninase, continuously depletes methionine within tumors and blocks tumor growth
