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PLP is a cofactor for the synthesis of several neurotransmitters including serotonin, the catecholamines dopamine, norepinephrine, and epinephrine [critical enzyme is aromatic L-amino acid decarboxylase (AADC) which is encoded by the DDC gene and is more commonly referred to as DOPA decarboxylase], and -aminobutyric acid, GABA (critical enzyme is glutamic acid decarboxylase, GAD)

That creates confusion for everyone involved

TABLE 2 Clinically identified missense NADSYN mutations in individuals diagnosed with CNDD

G., and Pinderski C

[DOI] [PubMed] [Google Scholar] 4.Stenson, et al

Nevertheless, this compound was temporarily banned by the World Anti-Doping Agency (WADA) in 2022 (it is not currently listed as banned by the WADA)