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10.3390/antiox11122475 14

The 5xFAD transgenic mouse line has been genetically engineered to model features of AD through the expression of human amyloid precursor protein (APP) and presenilin-1 transgenes, which are associated with earlyonset AD [21]
, Zhang, Q

52 In dendritic cells (DCs), SIRT1 modulates autophagy and cytokine secretion, enhancing antiviral responses while preventing excessive Th2/Th17-mediated inflammatory reactions

Mostly importantly, our findings should motivate longitudinal studies using 7T MRS to follow neurochemical changes in individual patents across the phases of their illness

10.1093/toxsci/kfm148 112 MeolaJ.RosaE.SilvaJ
