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The high Ca 2+ level in cytoplasm with mitochondria dysfunction and the low intracellular NAD + level both leads to the Warburg effect

Low dietary supply through a vegetarian or vegan diet

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Normal intramuscular dose of vitamin B12

To further reduce contamination risks, aliquot the reconstituted solution into sterile microtubes and label each one with the contents, concentration, and reconstitution date

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