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In addition, some exosomes improved the drug delivery efficiency by increasing the BBB membrane fluidity

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Doses used were well tolerated by patients, while only mild adverse effects were reported (heartburn, nausea, flatulence) [60]

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54 Moreover, polymeric NPs that originated from human serum albumin, poly(alkyl cyanoacrylate), poly(lactide-co-glycolide) and chitosan exhibited improved control of the drug delivery process