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It occurs when the immune system produces antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TgAb), leading to gradual destruction of thyroid tissue and progressive hypothyroidism

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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Hecker P.A., Leopold J.A., Gupte S.A., Recchia F.A., Stanley W.C

Intracellular GSH depletion enforces mitochondrial damage and causes cell death

Urol.,1968, 99, 980-985 20