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By blocking NNMT, 5-Amino-1MQ prevents the wasting of methyl groups

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Ulanovskaya OA, Zuhl AM, Cravatt BF. NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. Nat Chem Biol. 2013 May;9(5):300-6. doi: 10.1038/nchembio.1204. Epub 2013 Mar 3. PMID: 23455543; PMCID: PMC3631284

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