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We recently reported that NNMTi treatment combined with a low-fat, or lean, diet (LD) returned systemic adiposity and liver pathologies of obese animals to the adiposity and liver pathology levels of LD controls

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Here are two of the most notable experiments to date: In an 11-day study, obese mice treated with 20mg/kg of 5-amino-1MQ trice daily experienced a 5.1% weight reduction from baseline, while control mice gained 1.4% in body weight